বহুনির্বাচনি (MCQ)
১. The commonest cause of Down syndrome is:
ক) Robertsonian translocation
খ) Mosaicism
গ) Meiotic non-disjunction (trisomy 21)
ঘ) Deletion of chromosome 21
ঙ) Paternal age
উত্তর দেখুন
সঠিক উত্তর: গ) Meiotic non-disjunction (trisomy 21)
ব্যাখ্যা: About 95% of cases are trisomy 21 from maternal meiotic non-disjunction, linked with increasing maternal age; about 4% are translocations and 1% mosaics.
📖 রেফারেন্স: Robbins & Cotran, Pathologic Basis of Disease · Genetic disorders: cytogenetic disorders
